We conclude that the MA framework and conclusions have had an impact on environment and biodiversity policy and science in the UK, EU and internationally, but they have had little impact on other areas of policy and science. We suggest that if the MA is to have maximum impact it must influence sectors like the international development cooperation, trade, and financial sectors. We recommend that a UK Assessment report could be a useful exercise for testing the assumptions of the MA models and current knowledge of UK drivers of ecological change, and could provide a helpful model for other countries. Finally we suggest priorities for international and UK follow-up.