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Poxvirus research after smallpox eradication: new findings with an old vaccine

Prize lecture

Overview

Green fluorescent protein-tagged vaccinia virus spreading across cells. © Michael S Hollinshead

Leeuwenhoek Lecture 2020 given by Professor Geoffrey L. Smith FRS.

In 1980 smallpox was declared eradicated after a global vaccination campaign. Today, only two labs in the world retain variola virus, the cause of smallpox, one in the USA and one in Russia – and the World Health Assembly has recommended these virus stocks be destroyed when essential research with variola virus is complete.

Professor Geoffrey L. Smith FRS, winner of the 2020 Leeuwenhoek Medal, will describe how smallpox was eradicated and what happened afterwards. Despite eradication, research with vaccinia virus, the smallpox vaccine, has endured. This research has provided new ways to make vaccines, and revealed how our cells respond to virus infection and how the virus escapes these defenses. 

Attending this event

This lecture was originally scheduled for March 2020 and has now been rescheduled to take place online. Please follow the Register link above to book via Eventbrite, and we will send you joining details the week of the event. 

The award

The Leeuwenhoek Medal and Lecture was originally established to recognise excellence in the field of microbiology but now also includes excellence in bacteriology, virology, mycology and parasitology, and microscopy. The lectureship was named after the Dutch microscopist Antonie van Leeuwenhoek FRS, often referred to as the ‘Father of Microbiology’, and is supported by a bequest from George Gabb. Originally it was held annually, and from 2006 to 2018 it was awarded triennially, but it is now awarded biennially. The lecture was first given in 1950. The medal is of bronze, is awarded biennially and is accompanied by a gift of £2,000.

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Poxvirus research after smallpox eradication: new findings with an old vaccine

Leeuwenhoek prize lecture 2020 given by Professor Geoffrey L Smith FMedSci FRS.

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