Oct 6, 2009 - The presence of bone-marrow-derived stem cells was investigated in a wound-healing model where subcutaneously implanted cellulose sponges were used to induce granulation tissue formation. When cellulose was coated with hydroxyapatite (HA), the

Miretta Tommila, Anne Jokilammi, Perttu Terho, Timothy Wilson, Risto Penttinen, Erika Ekholm

Feb 19, 2007 - Drosophila neuroblasts are similar to mammalian neural stem cells in their ability to self-renew and to produce many different types of neurons and glial cells. In the past two decades, great advances have been made in understanding the molecular

Boris Egger, James M Chell, Andrea H Brand

Aug 6, 2019 - An excessive foreign body response (FBR) has contributed to the adverse events associated with polypropylene mesh usage for augmenting pelvic organ prolapse surgery. Consequently, current biomaterial research considers the critical role of the FBR

Shayanti Mukherjee, Saeedeh Darzi, Kallyanashis Paul, Jerome A. Werkmeister, Caroline E. Gargett

Oct 19, 2015 - Stem cell-based therapy is currently tested in several trials of chronic heart failure. The main question is to determine how its implementation could be extended to common clinical practice. To fill this gap, it is critical to first validate the

Philippe Menasché

Nov 25, 2008 - In recent years, the potential of stem cell research for tissue engineering-based therapies and regenerative medicine clinical applications has become well established. In 2006, Chung pioneered the first entire organ transplant using adult stem

Mark R Placzek, I-Ming Chung, Hugo M Macedo, Siti Ismail, Teresa Mortera Blanco, Mayasari Lim, Jae Min Cha, Iliana Fauzi, Yunyi Kang, David C.L Yeo, Chi Yip Joan Ma, Julia M Polak, Nicki Panoskaltsis, Athanasios Mantalaris

Dec 7, 2011 - Mechanical stimulation is an essential factor affecting the metabolism of bone cells and their precursors. We hypothesized that vibration loading would stimulate differentiation of human adipose stem cells (hASCs) towards bone-forming…

Laura Tirkkonen, Heidi Halonen, Jari Hyttinen, Hannu Kuokkanen, Harri Sievänen, Anna-Maija Koivisto, Bettina Mannerström, George K. B. Sándor, Riitta Suuronen, Susanna Miettinen, Suvi Haimi

Dec 4, 1984 - Recombinant genes can be introduced into the germ line of mice by microinjection into the fertilized egg or via embryonal carcinoma stem cells. A regulated, cell-type specific expression of the newly introduced gene following microinjection is

Jan 5, 2013 - The differentiation and reprogramming of cells are accompanied by drastic changes in the epigenetic profiles of cells. Waddington's classical model clearly describes how differentiating cells acquire their cell identity as the…

Akira Watanabe, Yasuhiro Yamada, Shinya Yamanaka

May 29, 2004 - The thesis advanced in this essay is that stem cells—particularly those in the nervous system—are components in a series of inborn ‘programs’ that not only ensure normal development, but persist throughout life so as to maintain homeostasis

Jaime Imitola, Kook In Park, Yang D. Teng, Sahar Nisim, Mahesh Lachyankar, Jitka Ourednik, Franz-Josef Mueller, Rene Yiou, Anthony Atala, Richard L. Sidman, Mark Tuszynski, Samia J. Khoury, Evan Y. Snyder

Feb 23, 2007 - Cell therapy has been perceived as the main or ultimate goal of human embryonic stem (ES) cell research. Where are we now and how are we going to get there? There has been rapid success in devising in vitro protocols for differentiating human ES

Su-Chun Zhang, Xue-Jun Li, M Austin Johnson, Matthew T Pankratz