Jan 11, 2023 - Wolbachia are the most widely distributed intracellular bacteria, and their most common effect on host phenotype is cytoplasmic incompatibility (CI). A variety of models have been proposed to decipher the molecular mechanism of CI, among which the

Weihao Dou, Baofa Sun, Yunheng Miao, Dawei Huang, Jinhua Xiao

Nov 9, 2022 - The development of organisms and tissues is dictated by an elaborate balance between cell division, apoptosis and differentiation: the cell population dynamics. To quantify these dynamics, we propose a phylodynamic inference approach based on

Sophie Seidel, Tanja Stadler

Jun 28, 2019 - Low-intensity electric fields can induce changes in cell differentiation and cytoskeletal stresses that facilitate manipulation of osteoblasts and mesenchymal stem cells; however, the application times (tens of minutes) are of the order of

Ram Anand Vadlamani, Yaohui Nie, David A. Detwiler, Agni Dhanabal, Alan M. Kraft, Shihuan Kuang, Timothy P. Gavin, Allen L. Garner

Apr 6, 2020 - As the field of tissue engineering continues to advance rapidly, so too does the complexity of cell culture techniques used to generate in vitro tissue constructs, with the overall aim of mimicking the in vivo microenvironment. This complexity

H. W. Hoyle, L. A. Smith, R. J. Williams, S. A. Przyborski

Dec 5, 2022 - The founder cells of the gametes are primordial germ cells (PGCs). In mammals, PGCs are specified early during embryonic development, at the boundary between embryonic and extraembryonic tissue, long before their later residences, the gonads, have

Bernard A. J. Roelen, Susana M. Chuva de Sousa Lopes

Nov 5, 2017 - Already during early embryogenesis, before sex-specific hormone production is initiated, sex differences in embryonic development have been observed in several mammalian species. Typically, female embryos develop more slowly than their male siblings.

Edda G. Schulz

Mar 30, 2020 - Thousands of unfixed transposable element (TE) insertions segregate in the human population, but little is known about their impact on genome function. Recently, a few studies associated unfixed TE insertions to mRNA levels of adjacent genes, but

Clément Goubert, Nicolas Arce Zevallos, Cédric Feschotte

Jul 5, 2018 - Recent advances in the isolation of tissue-resident adult stem cells and the identification of inductive factors that efficiently direct differentiation of human pluripotent stem cells along specific lineages have facilitated the…

Sharmin Alhaque, Michael Themis, Hassan Rashidi

Feb 5, 2015 - Anchorage-dependent cells are of great interest for various biotechnological applications. (i) They represent a formidable production means of viruses for vaccination purposes at very large scales (in 1000–6000 l reactors) using microcarriers, and

Otto-Wilhelm Merten