Sep 7, 2012 - The development of composite scaffolds with well-organized architecture and multi-scale properties (i.e. porosity, degradation) represents a valid approach for achieving a tissue-engineered construct capable of reproducing the medium- and long-term

Vincenzo Guarino, Francesco Urciuolo, Marco A. Alvarez-Perez, Benedetto Mele, Paolo A. Netti, Luigi Ambrosio

Dec 17, 1985 - The grasshopper central nervous system is composed of a brain and a chain of segmental ganglia. Each hemiganglion contains about 1000 neurons, most of which can be individually identified by their unique morphology and synaptic connectivity. Shortly

Aug 12, 2011 - Pluripotency is a transient cellular state during early development which can be recreated in vitro by direct reprogramming. The molecular mechanisms driving entry into and exit from the pluripotent state are the subject of intense research interest.

Thorold W. Theunissen, José C. R. Silva

Dec 17, 1985 - Studies of the role of cell lineage in development began in the latter part of the 19th century, fell into decline in the early part of the 20th, and were revived about 20 years ago. This recent revival was accompanied by the introduction of new and

Jun 15, 1988 - The detection of changes in mutation rate in human populations remains extremely difficult. Thus estimation of genetic hazards of mutagens to man depends on extrapolation from experimental systems. Germ cells of animals show complex variations in

Nov 28, 2005 - Understanding how the vertebrate central nervous system develops and functions is a major goal of a large body of biological research. This research is driven both by intellectual curiosity about this amazing organ that coordinates our conscious and

Katharine E Lewis

Nov 6, 2014 - The epigenetic pathway of a cell as it differentiates from a stem cell state to a mature lineage-committed one has been historically understood in terms of Waddington's landscape, consisting of hills and valleys. The smooth top and valley-strewn

Mithun K. Mitra, Paul R. Taylor, Chris J. Hutchison, T. C. B. McLeish, Buddhapriya Chakrabarti

Mar 19, 2014 - Major changes in intra- and extracellular pH homoeostasis are shared features of most solid tumours. These changes stem in large part from the metabolic shift of most cancer cells towards glycolytic metabolism and other processes associated with net

Anne Poder Andersen, José M. A. Moreira, Stine Falsig Pedersen