Dec 6, 2010 - Neovascularization or new blood vessel formation is of utmost importance not only for tissue and organ development and for tissue repair and regeneration, but also for pathological processes, such as tumour development. Despite this, the endothelial

Suzanne M. Watt, Athanasios Athanassopoulos, Adrian L. Harris, Grigorios Tsaknakis

Aug 31, 2016 - Three-dimensional (3D) computational tissue models can provide a comprehensive description of tissue dynamics at the molecular, cellular and tissue level. Moreover, they can support the development of hypotheses about cellular interactions and about

Torsten Thalheim, Peter Buske, Jens Przybilla, Karen Rother, Markus Loeffler, Joerg Galle

Dec 5, 2006 - Advanced therapies combating acute and chronic skin wounds are likely to be brought about using our knowledge of regenerative medicine coupled with appropriately tissue-engineered skin substitutes. At the present time, there are no models of an

Anthony D Metcalfe, Mark W.J Ferguson

Dec 5, 2014 - Mouse epiblast stem cells (EpiSCs) display temporal differences in the upregulation of Mixl1 expression during the initial steps of in vitro differentiation, which can be correlated with their propensity for endoderm differentiation. EpiSCs that

Keren Kaufman-Francis, Hwee Ngee Goh, Yoji Kojima, Joshua B. Studdert, Vanessa Jones, Melinda D. Power, Emilie Wilkie, Erdahl Teber, David A. F. Loebel, Patrick P. L. Tam

Oct 31, 2008 - KCNJ11-encoded Kir6.2 assembles with ATP-binding cassette sulphonylurea receptors to generate ATP-sensitive K+ (KATP) channel complexes. Expressed in tissues with dynamic metabolic flux, these evolutionarily conserved yet structurally and

Timothy J Nelson, Almudena Martinez-Fernandez, Andre Terzic

Jan 29, 2008 - Human mesenchymal stem cells (hMSCs) isolated from bone marrow aspirates were cultured on silk scaffolds in rotating bioreactors for three weeks with either chondrogenic or osteogenic medium supplements to engineer cartilage- or bone-like tissue

Alexander Augst, Darja Marolt, Lisa E Freed, Charu Vepari, Lorenz Meinel, Michelle Farley, Robert Fajardo, Nipun Patel, Martha Gray, David L Kaplan, Gordana Vunjak-Novakovic

Jul 31, 2006 - Recent work in neuroscience has shown that the adult central nervous system (CNS) contains neural progenitors, precursors and stem cells that are capable of generating new neurons, astrocytes and oligodendrocytes. While challenging the previous

U Shivraj Sohur, Jason G Emsley, Bartley D Mitchell, Jeffrey D Macklis

Oct 31, 2019 - Upon hydration and dehydration, the vegetative tissue of Selaginella lepidophylla can reversibly swell and shrink to generate complex morphological transformations. Here, we investigate how structural and compositional properties at tissue and cell

Véronique Brulé, Ahmad Rafsanjani, Meisam Asgari, Tamara L. Western, Damiano Pasini