241 - 250 of 656 results

Journal - Journal of The Royal Society Interface

Human endothelial stem/progenitor cells, angiogenic factors and vascular repair

Dec 6, 2010 - Neovascularization or new blood vessel formation is of utmost importance not only for tissue and organ development and for tissue repair and regeneration, but also for pathological processes, such as tumour development. Despite this, the endothelial

Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

Differential response of epiblast stem cells to Nodal and Activin signalling: a paradigm of early endoderm development…

Dec 5, 2014 - Mouse epiblast stem cells (EpiSCs) display temporal differences in the upregulation of Mixl1 expression during the initial steps of in vitro differentiation, which can be correlated with their propensity for endoderm differentiation. EpiSCs that

Journal - Journal of The Royal Society Interface

Stem cell competition in the gut: insights from multi-scale computational modelling

Aug 31, 2016 - Three-dimensional (3D) computational tissue models can provide a comprehensive description of tissue dynamics at the molecular, cellular and tissue level. Moreover, they can support the development of hypotheses about cellular interactions and about

Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

KCNJ11 knockout morula re-engineered by stem cell diploid aggregation

Oct 31, 2008 - KCNJ11-encoded Kir6.2 assembles with ATP-binding cassette sulphonylurea receptors to generate ATP-sensitive K+ (KATP) channel complexes. Expressed in tissues with dynamic metabolic flux, these evolutionarily conserved yet structurally and

Journal - Journal of The Royal Society Interface

Effects of chondrogenic and osteogenic regulatory factors on composite constructs grown using human mesenchymal stem

Jan 29, 2008 - Human mesenchymal stem cells (hMSCs) isolated from bone marrow aspirates were cultured on silk scaffolds in rotating bioreactors for three weeks with either chondrogenic or osteogenic medium supplements to engineer cartilage- or bone-like tissue

Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells

Jul 31, 2006 - Recent work in neuroscience has shown that the adult central nervous system (CNS) contains neural progenitors, precursors and stem cells that are capable of generating new neurons, astrocytes and oligodendrocytes. While challenging the previous