Aug 6, 2013 - For symmetrically dividing cells, large variations in the cell cycle time are typical, even among clonal cells. The consequence of this variation is important in stem cell differentiation, tissue and organ size…

Evgeny B. Stukalin, Ivie Aifuwa, Jin Seob Kim, Denis Wirtz, Sean X. Sun

Mar 23, 1987 - Three forms of viral hepatitis can be distinguished serologically. Hepatitis A virus is a picornavirus, which is being studied increasingly after its propagation in cell cultures. The B virus (HBV) is the prototype of a family now termed hepadna

Nov 5, 2013 - Asymmetric cell divisions (ACDs) result in two unequal daughter cells and are a hallmark of stem cells. ACDs can be achieved either by asymmetric partitioning of proteins and organelles or by asymmetric cell fate…

Anita Kulukian, Elaine Fuchs

Sep 27, 2019 - The unfolded protein response (UPR) is a collection of cellular feedback mechanisms that seek to maintain protein folding homeostasis in the endoplasmic reticulum (ER). When the ER is ‘stressed’, through either high protein folding demand or

Wylie Stroberg, Justin Eilertsen, Santiago Schnell

Nov 6, 2014 - The encapsulation of living mammalian cells within a semi-permeable hydrogel matrix is an attractive procedure for many biomedical and biotechnological applications, such as xenotransplantation, maintenance of stem cell phenotype and bioprinting of

Luca Gasperini, João F. Mano, Rui L. Reis

May 27, 2020 - Hutchinson–Gilford progeria syndrome (HGPS) is an ultra-rare disorder with devastating sequelae resulting in early death, presently thought to stem primarily from cardiovascular events. We analyse novel longitudinal cardiovascular data from a

S.-I. Murtada, Y. Kawamura, A. W. Caulk, H. Ahmadzadeh, N. Mikush, K. Zimmerman, D. Kavanagh, D. Weiss, M. Latorre, Z. W. Zhuang, G. S. Shadel, D. T. Braddock, J. D. Humphrey

Dr Philip Ball, winner of the 2022 Wilkins-Bernal-Medawar Medal, joins us to discuss human genome editing, and the importance of keeping historical and cultural perspectives visible in these debates. Our biotechnologies have entered uncharted

Dec 6, 2014 - Epithelial cells undergoing epithelial-to-mesenchymal transitions have often been shown to behave as cancer stem cells, but the precise molecular connection remains elusive. At the genetic level, stemness is governed by LIN28/let-7 double inhibition

Mohit Kumar Jolly, Bin Huang, Mingyang Lu, Sendurai A. Mani, Herbert Levine, Eshel Ben-Jacob