Feb 5, 2007 - The role of stem cells has long been known in reproductive organs and various tissues including the haematopoietic system and skin. During the last decade, stem cells have also been identified in other organs, including the nervous …

Jeffrey J Ross, Catherine M Verfaillie

Mar 28, 2008 - Haematopoietic stem cells (HSCs) can supply all blood cells throughout the adult life of individuals. Based on this property, HSCs have been used for bone marrow and cord blood transplantation. Among various stem…

Hideo Ema, Hiromitsu Nakauchi

May 29, 2004 - The fundamental basis of our work is that organs are generated by multipotent stem cells, whose properties we must understand to control tissue assembly or repair. Central nervous system (CNS) stem cells are now recognized as a…

R. D. McKay

Nov 21, 2006 - We present an optical imaging system and mathematical algorithms for three-dimensional sensing and identification of stem cells. Data acquisition of stem cells is based on holographic microscopy in the Fresnel domain by…

Inkyu Moon, Bahram Javidi

Jun 29, 1998 - The mammalian intestinal mucosa, with its distinctive polarity, high rate of proliferation and rapid cell migration, is an excellent model system to study proliferative hierarchies and the regulation of cell division, differentiation and cell death.

Christopher S. Potten

Dec 6, 2018 - The metaphor of a potential epigenetic differentiation landscape broadly suggests that during differentiation a stem cell approaches a stable equilibrium state from a higher free energy towards a stable equilibrium state which represents the final

K. Wiesner, J. Teles, M. Hartnor, C. Peterson

Jan 12, 2011 - Adult stem cells maintain the mature tissues of metazoans. They do so by reproducing in such a way that their progeny either differentiate, and thus contribute functionally to a tissue, or remain uncommitted and replenish the stem…

Gregory W. Charville, Thomas A. Rando