201 - 210 of 635 results

  • Genetically modified plants

    Genetically modified plants: questions and answers

  • Genetic technologies

    What can and should genetic technologies be used for?

  • Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

    Pluripotent stem cells: induction and self-renewal

    Jul 5, 2018 - Pluripotent stem cells (PSCs) lie at the heart of modern regenerative medicine due to their properties of unlimited self-renewal in vitro and their ability to differentiate into cell types representative of the three embryonic germ layers—mesoderm,

    Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

    Using stem cells to study and possibly treat type 1 diabetes

    Aug 12, 2011 - Stem cells with the potential to form many different cell types are actively studied for their possible use in cell replacement therapies for several diseases. In addition, the differentiated derivatives of stem

    Journal - Journal of The Royal Society Interface

    Physical confinement signals regulate the organization of stem cells in three dimensions

    Oct 31, 2016 - During embryogenesis, the spherical inner cell mass (ICM) proliferates in the confined environment of a blastocyst. Embryonic stem cells (ESCs) are derived from the ICM, and mimicking embryogenesis in vitro, mouse ESCs (mESCs) are often cultured in

    Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

    Present and future challenges of induced pluripotent stem cells

    Oct 19, 2015 - Growing old is our destiny. However, the mature differentiated cells making up our body can be rejuvenated to an embryo-like fate called pluripotency which is an ability to differentiate into all cell types by enforced expression of defined

    Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

    Progressing a human embryonic stem-cell-based regenerative medicine therapy towards the clinic

    Oct 19, 2015 - Since the first publication of the derivation of human embryonic stem cells in 1998, there has been hope and expectation that this technology will lead to a wave of regenerative medicine therapies with the potential to revolutionize our approach to

    Journal - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences

    From teratocarcinomas to embryonic stem cells

    Apr 29, 2002 - The recent derivation of human embryonic stem (ES) cell lines, together with results suggesting an unexpected degree of plasticity in later, seemingly more restricted, stem cells (so–called adult stem

    Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

    Immune response to stem cells and strategies to induce tolerance

    Jun 21, 2007 - Although recent progress in cardiovascular tissue engineering has generated great expectations for the exploitation of stem cells to restore cardiac form and function, the prospects of a common mass-produced cell resource for clinically viable

    Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

    Stem cell therapy: an exercise in patience and prudence

    Jan 5, 2013 - In recent times, the epigenetic study of pluripotency based on cellular reprogramming techniques led to the creation of induced pluripotent stem cells. It has come to represent the forefront of a new wave of alternative therapeutic approaches in the

    Journal - Interface Focus

    Mesenchymal stem cell-based bioengineered constructs: foreign body response, cross-talk with macrophages and impact of…

    Aug 6, 2019 - An excessive foreign body response (FBR) has contributed to the adverse events associated with polypropylene mesh usage for augmenting pelvic organ prolapse surgery. Consequently, current biomaterial research considers the critical role of the FBR

    Journal - Journal of The Royal Society Interface

    Metabolomics: a valuable tool for stem cell monitoring in regenerative medicine

    Aug 7, 2012 - Metabolomics is a method for investigation of changes in the global metabolite profile of cells. This paper discusses the technical application of the approach, considering metabolite extraction, separation, mass spectrometry and data interpretation.