201 - 210 of 635 results

  • Genetically modified plants

    Genetically modified plants: questions and answers

  • Genetic technologies

    What can and should genetic technologies be used for?

  • Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

    Induced pluripotent stem cells: opportunities and challenges

    Aug 12, 2011 - Somatic cells have been reprogrammed into pluripotent stem cells by introducing a combination of several transcription factors, such as Oct3/4, Sox2, Klf4 and c-Myc. Induced pluripotent stem (iPS) cells from a…

    Journal - Journal of The Royal Society Interface

    Genomic expression of mesenchymal stem cells to altered nanoscale topographies

    Feb 12, 2008 - The understanding of cellular response to the shape of their environment would be of benefit in the development of artificial extracellular environments for potential use in the production of biomimetic surfaces. Specifically, the understanding of

    Journal - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences

    Genome manipulation in embryonic stem cells

    Feb 27, 1993 - Embryonic stem (ES) cells derived from pluripotent cells of the early mouse embryo provide a powerful tool for genome manipulation in mammals. Dominantly acting effects can be achieved by introducing constructs to misexpress or ectopically express a

    Journal - Journal of The Royal Society Interface

    Systems level approach reveals the correlation of endoderm differentiation of mouse embryonic stem cells with specific…

    Jun 6, 2014 - Stem cells receive numerous cues from their associated substrate that help to govern their behaviour. However, identification of influential substrate characteristics poses difficulties because of their complex nature. In this study, we developed an

    Journal - Journal of The Royal Society Interface

    Characterization of the interface between adsorbed fibronectin and human embryonic stem cells

    Jun 6, 2013 - The cell–substrate interface plays a key role in the regulation of cell behaviour. Defining the properties of this interface is particularly important for human embryonic stem (hES) cell culture, because changes in this environment …

    Journal - Journal of The Royal Society Interface

    Mesenchymal stem cell mechanobiology and emerging experimental platforms

    Jul 6, 2013 - Experimental control over progenitor cell lineage specification can be achieved by modulating properties of the cell's microenvironment. These include physical properties of the cell adhesion substrate, such as rigidity, topography and deformation

    Journal - Philosophical Transactions of the Royal Society B: Biological Sciences

    Intertwining extracellular nucleotides and their receptors with Ca2+ in determining adult neural stem cell survival,…

    Aug 5, 2016 - In the central nervous system (CNS), during both brain and spinal cord development, purinergic and pyrimidinergic signalling molecules (ATP, UTP and adenosine) act synergistically with peptidic growth factors in regulating the synchronized