Jul 31, 2017 - Polydimethylsiloxane (PDMS) is widely used in dynamic biological microfluidic applications. As a highly hydrophobic material, native PDMS does not support cell attachment and culture, especially in dynamic conditions. Previous covalent coating

Joni Leivo, Sanni Virjula, Sari Vanhatupa, Kimmo Kartasalo, Joose Kreutzer, Susanna Miettinen, Pasi Kallio

Jul 5, 2018 - Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in developed countries. An in vitro NAFLD model would permit mechanistic studies and enable high-throughput therapeutic screening. While hepatic cancer-derived cell

Marcus J. Lyall, Jessy Cartier, John P. Thomson, Kate Cameron, Jose Meseguer-Ripolles, Eoghan O'Duibhir, Dagmara Szkolnicka, Baltasar Lucendo Villarin, Yu Wang, Giovanny Rodriguez Blanco, Warwick B. Dunn, Richard R. Meehan, David C. Hay, Amanda J. Drake

Feb 20, 2007 - The anticipated therapeutic uses of neural stem cells depend on their ability to retain a certain level of developmental plasticity. In particular, cells must respond to developmental manipulations designed to specify precise neural fates. Studies

Nicholas D Allen

Jul 31, 2006 - Diseases of the brain and spinal cord represent especially daunting challenges for cell-based strategies of repair, given the multiplicity of cell types within the adult central nervous system, and the precision with which they must interact in both

Steven A Goldman, Martha S Windrem

Jul 19, 2015 - Peto's paradox is the lack of the expected trend in cancer incidence as a function of body size and lifespan across species. The leading hypothesis to explain this pattern is natural selection for differential cancer prevention in larger, longer

Robert Noble, Oliver Kaltz, Michael E. Hochberg

Jul 6, 2014 - Urological reconstructive surgery is sometimes hampered by a lack of tissue. In some cases, autologous urothelial cells (UCs) are not available for cell expansion and ordinary tissue engineering. In these cases, we wanted to explore whether

J. Zhao, S. Zeiai, Å. Ekblad, A. Nordenskjöld, J. Hilborn, C. Götherström, M. Fossum