Jul 5, 2018 - Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in developed countries. An in vitro NAFLD model would permit mechanistic studies and enable high-throughput therapeutic screening. While hepatic cancer-derived cell

Marcus J. Lyall, Jessy Cartier, John P. Thomson, Kate Cameron, Jose Meseguer-Ripolles, Eoghan O'Duibhir, Dagmara Szkolnicka, Baltasar Lucendo Villarin, Yu Wang, Giovanny Rodriguez Blanco, Warwick B. Dunn, Richard R. Meehan, David C. Hay, Amanda J. Drake

Jul 19, 2015 - Peto's paradox is the lack of the expected trend in cancer incidence as a function of body size and lifespan across species. The leading hypothesis to explain this pattern is natural selection for differential cancer prevention in larger, longer

Robert Noble, Oliver Kaltz, Michael E. Hochberg

Sep 30, 2020 - Disease response and durability of remission are very heterogeneous in patients with acute myeloid leukaemia (AML). There is increasing evidence that the individual risk of early relapse can be predicted based on the initial treatment response.

H. Hoffmann, C. Thiede, I. Glauche, M. Bornhaeuser, I. Roeder

Nov 7, 2012 - The cell walls in plants are made up of just four basic building blocks: cellulose (the main structural fibre of the plant kingdom) hemicellulose, lignin and pectin. Although the microstructure of plant cell walls varies in different types of plants,

Lorna J. Gibson

May 13, 2020 - The cuticle of ecdysozoans (Panarthropoda, Scalidophora, Nematoida) is secreted by underlying epidermal cells and renewed via ecdysis. We explore here the relationship between epidermis and external cuticular ornament in stem-group scalidophorans

Deng Wang, Jean Vannier, Xiao-guang Yang, Jie Sun, Yi-fei Sun, Wen-jing Hao, Qing-qin Tang, Ping Liu, Jian Han

May 22, 1982 - Three main types of colony forming epithelial cell, termed elongated, cuboidal and open, are found in cultures of human milk. Subculture of identified colonies, and cloning from single cells shows that each cell type can maintain…

Jun 24, 2020 - Human mesenchymal stromal cells (MSCs) are a leading cell therapy candidate for the treatment of immune and inflammatory diseases due to their potent regulation of immune cells. MSC expression of indoleamine-2,3-dioxygenase (IDO) upon interferon γ

Devlin T. Boyt, Lauren K. Boland, BurandAnthony J. Jr, Alex J. Brown, James A. Ankrum