Oct 19, 2015 - Nuclear transfer that involves the transfer of the nucleus from a donor cell into an oocyte or early embryo from which the chromosomes have been removed was considered first as a means of assessing changes during development in the ability of the

Ian Wilmut, Yu Bai, Jane Taylor

Apr 30, 2018 - The development of assays for evaluating the sensitivity of leukaemia cells to anti-cancer agents is becoming an important aspect of personalized medicine. Conventional cell cultures lack the three-dimensional (3D) structure of the bone marrow (BM),

Mahroo Karimpoor, Eva Yebra-Fernandez, Maryam Parhizkar, Mine Orlu, Duncan Craig, Jamshid S. Khorashad, Mohan Edirisinghe

Oct 12, 2020 - Advances in fluorescence microscopy approaches have made it relatively easy to generate multi-dimensional image volumes and have highlighted the need for flexible image analysis tools for the extraction of quantitative information from such data.

Karolis Leonavicius, Christophe Royer, Antonio M. A. Miranda, Richard C. V. Tyser, Annemarie Kip, Shankar Srinivas

Aug 6, 2020 - Animal tissue requires low-oxygen conditions for its maintenance. The need for low-oxygen conditions contrasts with the idea of an evolutionary leap in animal diversity as a result of expanding oxic conditions. To accommodate tissue renewal at oxic

Emma U. Hammarlund

Jan 7, 2012 - World Health Organization estimated that heart failure initiated by coronary artery disease and myocardial infarction (MI) leads to 29 per cent of deaths worldwide. Heart failure is one of the leading causes of death in industrialized countries and

Jayarama Reddy Venugopal, Molamma P. Prabhakaran, Shayanti Mukherjee, Rajeswari Ravichandran, Kai Dan, Seeram Ramakrishna

Mar 12, 1990 - As part of our attempts to understand principles that underly organism development, we have been studying the development of the rat optic nerve. This simple tissue is composed of three glial cell types derived from two distinct cellular lineages.

Dec 5, 2014 - Embryonic stem (ES) cells are characterized by their functional potency and capacity to self-renew in culture. Historically, ES cells have been defined as pluripotent, able to make the embryonic but not the extraembryonic lineages (such as the yolk

Sophie M. Morgani, Joshua M. Brickman

Jun 29, 2002 - Arabidopsis leaf hairs (trichomes) are polyploid epidermal cells with a predictable branching pattern. More than 15 genes have been identified that are involved in the regulation of branching. The cloning of the ZWICHEL, ANGUSTIFOLIA and STICHEL

A. Schnittger, M. Hülskamp