Jun 1, 2021 - Anne Warner applied physiological techniques to developmental biology, elucidating the mechanisms of cell interaction and communication that pattern the early embryo. Through her determination and passion for science, she contributed crucial

Sarah Guthrie

Apr 30, 2018 - The development of assays for evaluating the sensitivity of leukaemia cells to anti-cancer agents is becoming an important aspect of personalized medicine. Conventional cell cultures lack the three-dimensional (3D) structure of the bone marrow (BM),

Mahroo Karimpoor, Eva Yebra-Fernandez, Maryam Parhizkar, Mine Orlu, Duncan Craig, Jamshid S. Khorashad, Mohan Edirisinghe

May 22, 1982 - Three main types of colony forming epithelial cell, termed elongated, cuboidal and open, are found in cultures of human milk. Subculture of identified colonies, and cloning from single cells shows that each cell type can maintain…

Oct 19, 2015 - Nuclear transfer that involves the transfer of the nucleus from a donor cell into an oocyte or early embryo from which the chromosomes have been removed was considered first as a means of assessing changes during development in the ability of the

Ian Wilmut, Yu Bai, Jane Taylor

Jun 29, 1998 - The ability to process damaged DNA may vary between cells depending on their differentiated status. However, there is little in vivo data available and it is not intuitively obvious how the activity of specific repair pathways may vary between

Douglas J. Winton, Roger A. Brooks

Sep 5, 2014 - A strong correlation between centrosome age and fate has been reported in some stem cells and progenitors that divide asymmetrically. In some cases, such stereotyped centrosome behaviour is essential to endow stemness to only one of the two daughters

Jose Reina, Cayetano Gonzalez

Jun 22, 1989 - The bog mosses, Sphagnum, lack any obvious anatomical specialization inside the stem but have a well-developed system of water conduction in capillary spaces among pendent branches around the stem. It has hitherto been assumed that this was the main

Apr 30, 2017 - In this review, we discuss recent developments in the field of nanoparticles and their use in tissue regeneration approaches. Owing to their unique chemical properties and flexibility in design, nanoparticles can be used as drug delivery systems, to

Sabine van Rijt, Pamela Habibovic

Apr 24, 2019 - Arm loss through a separation at a specialized autotomy plane in echinoderms is inextricably linked to regeneration, but the link between these phenomena is poorly explored. We investigated nervous system regeneration post-autotomy in the asteriid

Maria Byrne, Franca Mazzone, Maurice R. Elphick, Michael C. Thorndyke, Paula Cisternas