Aug 30, 1994 - Our previous studies have shown that haemopoietic stem cells undergo apoptotic death as a consequence of growth factor withdrawal. In this paper we review the new data that has accumulated since this observation and compare it with older data from

Aug 19, 2016 - Differentiation within multicellular organisms is controlled by epigenetic markers transmitted across cell division. The process of differentiation will modify these epigenetic markers so that information that one cell type possesses can be lost in

Michael Lachmann, Eric Libby

Aug 30, 1994 - The major disseminated cancers remain stubbornly resistant to systemic therapy. Drug-resistant tumours include both slow and fast growing types, with the carcinomas constituting the major problem. Strategies for drug discovery have, in the past,

Nov 19, 1980 - Mouse cells stably transformed by simian virus 40 (SV40) contain viral DNA covalently integrated into their chromosomal DNA. We have used molecular cloning techniques to isolate and characterize the integrated viral DNA, together with the flanking

Jun 10, 1981 - Plant protoplasts of several horticultural and crop species can now be readily regenerated into plants. There are now available several opportunities for their use in the manipulation of genetic systems in plant breeding. Protoplast cloning has

Apr 24, 2019 - Arm loss through a separation at a specialized autotomy plane in echinoderms is inextricably linked to regeneration, but the link between these phenomena is poorly explored. We investigated nervous system regeneration post-autotomy in the asteriid

Maria Byrne, Franca Mazzone, Maurice R. Elphick, Michael C. Thorndyke, Paula Cisternas

Jan 1, 1906 - In a paper published in 1900 a description was given of certain pathological outgrowths, first called intumescences by Sorauer, but known as œdemata to American writers, occurring spontaneously on Hibiscus vitifolius, Linn. The paper is mainly

Jan 5, 2018 - During metastasis, tumour cells must communicate with their microenvironment by secreted soluble factors and extracellular vesicles. Different stromal cell types (e.g. bone marrow–derived cells, endothelial cells and fibroblasts)…

Lucía Robado de Lope, Olwen Leaman Alcíbar, Ana Amor López, Marta Hergueta-Redondo, Héctor Peinado

Jul 19, 2015 - Antagonistic coevolution between maternal and fetal genes, and between maternally and paternally derived genes may have increased mammalian vulnerability to cancer. Placental trophoblast has evolved to invade maternal tissues and evade structural

David Haig